Ukwelapha i-aspergillosis, kulokhu, i-aspergillosis ehlasela kakhulu, ngemithi ye-antifungal inemikhawulo yayo. Avame ukuba nobuthi futhi kufanele asetshenziswe ngokucophelela ngodokotela abanolwazi. Lapho ukwelapha umuntu okhubazekile kakhulu ongenwe yigciwane I-Aspergillus (okuyiqembu elikhulu labantu abathola uhlobo oluyingozi lwalesi sifo) amazinga okufa angadlula ama-50% emaqenjini eziguli abelashelwa i-leukemia. Kulula ukubona ukuthi sidinga ukuthuthukisa izindlela zokwelapha ezingcono kanye namasu ahlukene okwelapha.

Iqembu labacwaningi baseJalimane eNyuvesi yaseWurtzburg, eliholwa uJurgan Loffler kanye noMichael Hudacek selamukele indlela ehluke ngokuphelele yokwelapha i-aspergillosis, esikhundleni sokwenza imithi ye-antifungal bakhethe 'ukuqeqesha' amasosha omzimba eziguli ezingenawo amandla omzimba ukuze zibone futhi zihlasele i-aspergillosis. ukutheleleka kangcono ngethemba lokuthi lokhu kuzothuthukisa ukufa.

Lobu buchwepheshe bukopishwe ocwaningweni lomdlavuza, lapho sazi khona ukuthi eminye imidlavuza ibalekela ukuhlasela amasosha omzimba futhi lokhu kuvumela umdlavuza ukuthi ukhule. Abacwaningi 'ukuqeqesha kabusha' ngempumelelo amasosha omzimba ukuhlasela amangqamuzana omdlavuza ngempumelelo.

Iqembu lathatha amaseli amasosha omzimba egundane (T-cells) avame ukuhlasela amagciwane asulelayo ukuze aqede izifo futhi athuthukise amandla awo okuthola. I-Aspergillus fumigatus, okuyi-pathogen eyinhloko ebangela i-aspergillosis. Lamaseli abe esenikwa amagundane angenwe yiwo I-Aspergillus uhlelo lwemodeli yegundane oluhloselwe ukulingisa i-aspergillosis ehlaselayo ezigulini ezingabantu.

Umphumela waba ukuthi kulawo magundane ayene-aspergillosis yamaphaphu futhi ayengenakwelashwa, ama-33% asala ephila kuyilapho kulawo magundane ebelashwe ngama-booster T-cells (CAR-T) angu-80% asinda.

Lo mphumela ubonisa isithembiso esikhulu sokwelashwa kwe-aspergillosis. Le miphumela yokuhlola idinga ukuphindaphindwa kumuntu ophethe kodwa kuyacaca ukuthi le ndlela ingaba yisisekelo sendlela entsha ngokuphelele yokwelapha i-aspergillosis, okuhlanganisa izinhlobo ezingamahlalakhona ze-aspergillosis njenge-chronic pulmonary aspergillosis (CPA) kanye mhlawumbe ne-allergic bronchopulmonary. i-aspergillosis (ABPA).

Iphepha eligcwele lishicilelwe lapha