I-Aspergillus amaqhubu
Uhlolojikelele
Amaqhuqhuva amaphaphu amachashaza amancane aminyene abonwa ku-X-ray noma ku-CT scan. Ezinye azinangozi, kodwa ezinye zidalwa izifo ezihlukahlukene ezihlanganisa izifo ezibangelwa amagciwane (isb. isifo sofuba), izifo zesikhunta (isb. I-Aspergillus), umdlavuza noma izifo ezithile ze-autoimmune. I-Aspergillus amaqhuqhuva adinga ukuqapha isikhathi eside, kodwa azinzile angase angadingi ukwelashwa
Izimpawu
Izimpawu ziyahlukahluka futhi kungaba nzima ukuzihlukanisa kulezo zezinye izimo ezivamile zamaphaphu (isb. CPA, COPD, bronchiectasis)
- Abanye abantu baba nezimpawu ezikhathazayo ezingaqondile (isb. Lesi kungaba isikhathi esabisa kakhulu nesididayo, ngakho-ke kungase kube usizo ukujoyina omunye wethu amaqembu asekela isiguli
- Amaqhuqhuva azinzile (angakhuli) angeke abangele noma yiziphi izimpawu - empeleni, abantu abaningi emhlabeni jikelele baphatha iqhuqhuva elilodwa noma ngaphezulu ngaphandle kokuqaphela.
Izimbangela
Amaqhuqhuva angakhula njengengxenye yesimo esiyinkimbinkimbi njenge-CPA, lapho kungase kube khona ukushiyeka okucashile ohlelweni lokuzivikela komzimba okwenza umuntu abe sengozini enkulu yezifo eziwukhunta.
Amaqhuqhuva angakheka futhi kubantu abaphile kahle, lapho izinhlamvu zesikhunta zihogelwa futhi umzimba wenza ungqimba oluvikelayo 'lwezicubu ze-granulation' ukuze luqukethe ukutheleleka.
Sifo
Ama-nodule avame ukubonwa kuqala kuma-CT scan. Ukuxilongwa kungase kube nzima ngoba amasiko esikhwehlela nokuhlolwa kwegazi (isb. I-Aspergillus I-IgG, precipitins) ngokuvamile ibuyisela umphumela ongemuhle. Izicubu zamaphaphu zingathathwa ngokwenza i-need biopsy, bese ihlolwa ngesibonakhulu ukuze kubhekwe izimpawu I-Aspergillus. Nokho, le nqubo iyingozi kakhulu.
Ukuze uthole ukwaziswa okwengeziwe I-Aspergillus ukuhlolwa chofoza lapha
Ukwelashwa
Akuwona wonke amaqhuqhuva adinga ukwelashwa kwe-antifungal - udokotela wakho angase ancome indlela yokulinda nokulinda ukuze agweme imiphumela emibi yale mithi enamandla. Uma i-nodule yakho ikhula, noma kuvela amasha, ungase unikezwe inkambo i-antifungal imithi efana ne-voriconazole
Amaqhuqhuva angawodwa angasuswa ngezikhathi ezithile ngokuhlinzwa, bese kuthi ama-antifungal anikezwe izinyanga ezithile ukuvimbela ukuphindeka.
Isibikezelo
Ngeshwa kunzima kakhulu ukubikezela ukuthi amaqhuqhuva azoziphatha kanjani ngokuhamba kwesikhathi, ikakhulukazi kubantu lapho imbangela eyisisekelo ingacacile. Ama-nodule amaningi ahlala ezinzile iminyaka eminingi futhi agadwa nje ukuze kutholakale izinguquko. Ezinye ziyashwabana, kuyilapho ezinye zikhula futhi zingase zivele ezintsha. Abanye baqhubeka nokwenza umgodi ogcwele imfucumfucu yesikhunta (‘aspergilloma’) kanti ezinye iziguli ekugcineni zizotholakala CPA
Ulwazi olunzulu
Ngeshwa luncane ulwazi mayelana nezigaxa zokukhunta olutholakalayo ngoba kuyisifo esingandile futhi esingafundwanga kangako. Qaphela kakhulu ngolwazi oluthola ku-inthanethi - kunolwazi oluningi olungaqondile ezinkundleni zokuxhumana, oluncoma ngezinye izikhathi ukudla okungaphephile kanye nezithako zokudla.
I-NAC ishicilele iphepha lesayensi (www.ncbi.nlm.nih.gov/pmc/articles/PMC4991006) mayelana I-Aspergillus izigaxana ezibonwa emtholampilo wethu siqu, ongazifunda ku-inthanethi noma wabelane nodokotela wakho.