Aspergillosis Murwere & Muchengeti Tsigiro

Yakapihwa neNHS National Aspergillosis Center

World Aspergillosis Day 2022

– Semina Series
– Nyaya dzevarwere
– Mubvunzo & Mhinduro

National Aspergillosis Center Semina Series 2022

 

Gore rino reWorld Aspergillosis Day, National Aspergillosis Center yakaita hurukuro dzakatevedzana kubva kuvarapi nevarwere nezve aspergillosis. Chiitiko ichi chakabudirira zvinokatyamadza (kunyangwe paine mashoma mashoma ehunyanzvi), paine vanhu 160 vakapinda zuva rese kuhurukuro dzakasiyana siyana.
 

Pazasi pane hurukuro dzakarekodhwa uye PowerPoint mharidzo kubva pazuva.

Munguva yehurukuro, takapa sarudzo yekubvunza mibvunzo muZoom chat. Kana mushure mekunge maona vhidhiyo yemusangano yakarekodhwa newewo kuda kubvunza mubvunzo ndapota taura nesu pa NAC.Cares@mft.nhs.uk

 

 

Iyo National Aspergillosis Center yakatanga sei Chris Harris, Maneja weNAC

Ndiani anowana aspergillosis? Caroline Baxter, NAC Clinical Lead

Tingaona sei aspergillosis? Lily Novak Frazer, MRCM (diagnostics)

Tingabata sei aspergillosis? Chris Kosmidis, NAC Consultant

 

Antifungal mishonga yakaoma kushandisa here? Fiona Lynch, Nyanzvi yemishonga

 

Kubatsira varwere kurarama neaspergillosis Phil Langridge naMairead Hughes, Nyanzvi yeAspergillosis Physiotherapists & Jenny White, Aspergillosis Nyanzvi Mukoti

Nyaya dzevarwere: Kurarama ne aspergillosis

Nyaya dzakatevedzana kubva kuvarwere vana, umo vanokurukura nezvekuongorora, maitiro uye manejimendi. Nyaya dzedu dzese dzevarwere dzinogona kuwanikwa pano. 

MFIG yekutsvaga muManchester Angela Brennan

MRC Center for Medical Mycology, Aspergillosis Tsvakurudzo, Elaine Bignell

 

European Lung Foundation Kutsigira varwere, kusanganisira varwere mukutsvaga muEurope yose

Chikwata cheNAC CARES 

 

Nhau dzevarwere

Aspergillosis chirwere chinopedza simba uye chehupenyu hwose uye kuongororwa kunoshandura hupenyu. Kurondedzera nyaya dzemurwere chinhu chakakosha mukusimudzira ruzivo. Nyaya idzi hadzisi chete dzinobatsira vamwe vane chirwere ichi kunzwa sekunge havasi vega, asi zvakare dzinopa varwere simba uye dzinopa ruzivo rwakakosha muruzivo rwemurwere kune varapi nevashandi vehutano.

Mavhidhiyo ari pasi apa anotaura nyaya dzevarwere vana, mumwe nomumwe achirarama nemhando yakasiyana yeAspergillosis.

 

Ian - Invasive Aspergillosis yeCentral Nervous System (CNS)

Unogona kuwana rumwe ruzivo nezve Invasive CNS Aspergillosis pano.

Alison - Allergic Bronchopulmonary Aspergillosis (ABPA).

Unogona kuwana rumwe ruzivo nezve ABPA pano. 

Mick – Chronic Pulmonary Aspergillosis (CPA).

Unogona kuwana mamwe mashoko pamusoro CPA pano. 

Gwynedd - Chronic Pulmonary Aspergillosis (CPA) Allergic Bronchopulmonary Aspergillosis (ABPA)

 

Q&A

Q. Ko SAFS inogona kushanduka kuita APBA.?

Asthma Yakanyanya ine Fungal Sensitization (SAFS) inoita seinosiyana neAllergic Bronchopulmonary Aspergillosis (ABPA) pakuti varwere veSAFS havatamburi nemucoid impaction kana bronchiectasis, uye varwere vane ABPA havafanirwe kuve neasthma yakanyanya.
Dzimwe SAFS dzinogona kukura kuita ABPA? Parizvino isu hatisati tine humbowo hwakawanda hwekusarudza imwe nzira kana imwe, asi sezvo SAFS iri mamiriro achangobva kuzivikanwa zvinogona kutora makore akawanda kuti tive nechokwadi, saka hatigone kuzvibvisa zvachose.

 

Q. Unowana nyaya dzeTB & IA coinfection?

Ndinofungidzira kuti uri kureva TB uye Chronic Pulmonary Aspergillosis (CPA) sezvo zviviri izvi zvakanyatsobatanidzwa? Vaviri vacho vanogona kugarisana uye kutapurira muenzi mumwechete - zvakataurwa pane imwe yehurukuro masikati ano.
IA (Invasive aspergillosis) chirwere chevanhu vasina immunocompromised avo vanowanzova vanhu vane masoja ekudzivirira emuviri akakanganiswa zvakanyanya eg vanogamuchira vanoisirwa.

 

Mubvunzo

ATCC sezvo pasina kutyora kweanti fungal yeATCC

 

Q. Ko ABPA "kufambira mberi" uye kushanduka kuva CPA/IA? Kuve murwere weABPA ivo vanotorawo kuongororwa ropa kwemazinga angu egalactomannan.

Nhamba diki dzeAllergic Bronchopulmonary Aspergillosis (ABPA) varwere vanofambira mberi kuita mapapu emapapu (Chronic Pulmonary Aspergillosis). Chinhu chatinoramba tichiongorora panguva yekushanya kukiriniki kwevanhu vatinofunga kuti vanogona kunge vari panjodzi.

 

Mubvunzo

Zviitiko zvizhinji (>90%) zvinogadziriswa kana itraconazole yambomiswa kwemwedzi. https://pubmed.ncbi.nlm.nih.gov/21685202/

 

Q. Letrozole kupindirana ne antifungals

Hapana chakacherechedzwa - saka hatigone kuramba kuti panogona kunge paine vamwe asi hazvina kutaurwa - maona https://antifungalinteractions.org/

 

Q. Ndiri muboka revanhu vakataurwa naDr Baxter vasina mamwe mamiriro ekufema kana mamwe alergy anozivikanwa. Muongorori wangu akataura kuti inogona kunge iri genetic in causation. Izvi zvingangoitika here? pane tsvakurudzo here mune izvi?

Tichifunga kuti une ABPA sekureva kwawakaita allergies, pane mashoma genetic maitiro akaonekwa ane zvimwe zvinouya.