Vhidhiyo kubvunzurudzwa nemurwere ane aspergilloma uye asingaperi pulmonary aspergillosis, akaonekwa mushure mekukosora ropa uyo akazogadzira azole resistance pa voriconazole. Nhoroondo Yemurwere Murwere uyu aive nekyphoscoliosis yakaoma semwana nekuiswa kwepinal rods mukukura kwekutanga. Anogara kwenguva refu asingasvuti. Akatanga kuburitsa muna 2001 aine chikosoro chinogumbura uye marapiro akati wandei nemishonga inorwisa mabhakitiriya akatadza kuchipedza. Mushure memakore maviri chikosoro chakawedzera uye akatanga kupisa muviri. Akaferefetwa asi maresults aive asina kukwana. Akabva akosora ropa rakawanda (hemoptysis) ndokubuda ropa rakanyanyisa iro rakarapwa ne embolisation uye oral tranexamic acid. Akaramba achikosora achiburitsa sputum yegreen nekuwonda. Aspergillus precipitin titre yaive yakakwira uye pakutanga akaonekwa aine chronic pulmonary aspergillosis negonzo rimwe raive neaspergilloma. Kurapwa neitraconazole hakuna kuderedza zviratidzo zvake (zvisinei nehuwandu hweropa hwakakwana) uye akatanga voriconazole uye kuvandudzwa kwakanyanya kwakaonekwa pakutanga uye akawedzera huremu. Akaramba ari voriconazole kwemakore maviri. Zvisinei Aspergillus titre yake yakaramba yakakwira uye kukosora kwakaramba kuchienderera. Mimwe miedzo yakaratidza kuti plasma mazinga evoriconazole anodarika 2mg/L, zvisinei kuti masotes akaburitsa kuti Aspergillus fumigatus yake yakanga isingaite zvinodhaka kune itraconazole, voriconazole uye posaconazole. Murwere parizvino akatanga kurapa amphotericin B. Tinotenda murwere nekupa nemutsa hurukuro iyi.