Immunoglobulins, inozivikanwawo sema antibodies, mapuroteni anogadzirwa ne immune system mukupindura kuvapo kwezvinhu zvekunze, senge mavhairasi uye mabhakitiriya. Kune marudzi akasiyana ema immunoglobulins, anosanganisira IgG uye IgE, ayo anoita mabasa akasiyana mu immune system. Muaspergillosis, ese maIgG neIgE masoja ekudzivirira chirwere anoita mabasa akakosha mukupindura kwedziviriro kune Aspergillus fungus. Ichi chinyorwa chine chinangwa chekupa ruzivo rwakakosha nezve mutsauko uripo pakati peIgG neIgE.
Chii chinonzi IgG?
IgG ndiyo yakajairika mhando yeimmunoglobulin muropa, inoverengera inosvika makumi manomwe neshanu muzana emasoja ekudzivirira emuviri mumuviri. IgG inoita basa rakakosha mukurwisa hutachiona hwehutachiona uye hwehutachiona uye inobatanidzwawo mukupindura kwemuviri kune mamwe marudzi ekenza maseru. IgG inogona kuyambuka placenta uye inopa dziviriro kumwana ari kukura, ndosaka ichinzi "antibody yaamai."
Akakwira mazinga eIgG masoja ekudzivirira chirwere kuAspergillus anowanzoonekwa mune vanhu vane Chronic Pulmonary Aspergillosis (CPA), uye kuyera IgG antibody mazinga chinhu chakakosha chekuongorora chemamiriro ezvinhu.
Chii chinonzi IgE?
IgE imhando ye immunoglobulin inoita basa mukupindura kweallergic. IgE inogadzirwa mukupindura kuratidzwa kune zvinokonzeresa, senge pollen, mvere dzemhuka, uye chimwe chikafu, uye kune varwere vane allergic bronchopulmonary aspergillosis - aspergillus fungus. Kana IgE inosunga kune allergen, inokonzeresa kuburitswa kwehistamine nemamwe makemikari, zvichitungamira kune zviratidzo zvekusawirirana, senge:
- Wheezing
- Kuchema
- Kupfupika kwemhepo
- Kurwadziwa pachifuva kana kuoma
Kusiyana pakati peIgG neIgE
Pane misiyano yakati wandei pakati peIgG neIgE, kusanganisira:
- IgG inoita basa mukurwisa hutachiona nehutachiona, nepo IgE ichibatanidzwa mukupindura kweallergic.
- IgG ine hafu yehupenyu hurefu muropa kupfuura IgE, zvinoreva kuti inogara mumuviri kwenguva refu.
- IgG inotora nguva yakareba kuti ibudise mukupindura hutachiona kana kuratidzwa kune antigen, nepo IgE inogadzirwa nekukurumidza mukupindura kune allergen.
Ose maIgG neIgE masoja ekudzivirira chirwere anoita mabasa akakosha mukupindura kwedziviriro muaspergillosis. Nepo IgG ichibatsira kudzikamisa uye kubvisa fungus, IgE inokonzeresa mhinduro uye inotungamira kune zviratidzo muvanhu vane Allergic Bronchopulmonary Aspergillosis (ABPA). Kuyera mazinga eantibody kuAspergillus kunogona kubatsira mukuongorora nekutarisa aya mamiriro.
Rumwe ruzivo nezve basa reIgE neIgG rinogona kuwanikwa kuburikidza nemalink ari pazasi:
https://onlinelibrary.wiley.com/doi/10.1111/all.14908
https://www.britannica.com/science/immune-system/Classes-of-immunoglobulins