Vazhinji vevanhu vanoenda kumakiriniki edu vane alergic mafomu easpergillosis semuenzaniso allergic bronchopulmonary aspergillosis (ABPA). ABPA inoratidzwa nehuwandu hwehuwandu hweIgE muropa izvo zvinokonzeresa zvakawanda zveallergic zviratidzo zvinonetsa kurarama nazvo. Kurapa nemishonga inonzi steroid (eg prednisolone) yakashandiswa kwemakumi emakore kuderedza huwandu hweIgE muropa revarwere veABPA uye nokudaro kuderedza zviratidzo, asi avo vakatora steroids vachaziva kuti mishonga iyoyo ine nhamba yemigumisiro isingafadzi zvakare. kuwedzera huremu, high blood pressure, mavanga, kusaona zvakanaka nezvimwe zvakawanda (ona NHS corticosteroid ruzivo )

Sezvineiwo vanachiremba vatanga kutsvaga nzira dzekudzikisa pamazinga ese eIgE uye steroid dose. Vazhinji vevarwere vedu vane ABPA vachapihwa mushonga weantifungal uyo unowanzo kuderedza IgE uye wozobvumira steroid dose kuti ideredzwe zvishoma nezvishoma nerubatsiro rwevanachiremba.

Kwenguva yakati zvave zvichigonekawo kuve nejekiseni remushonga unozivikanwa seXolair uye unogona kudzikisa zvakanyanya IgE mazinga, zvisinei haiwanzo shandiswa kurapa ABPA sezvo yakanyatsogadzirirwa kurapa yakanyanya asima. Xolair inogonawo dzimwe nguva kudzvanya immune system yevarwere zvishoma uye kukonzera hutachiona hwemapapu uye kune varwere vazhinji zvinonetsa kubata.

Zvinofadza kuti kune mishonga mitsva mukukura iyo inoshanda nenzira yakafanana neXolair saka ichaderedza kudiwa kwe steroids asi mishonga mitsva iyi inotarisa zvakananga IgE inokonzerwa nehutachiona hwefungal. Nekuda kweizvozvo ivo vanofanirwa kuve vakakodzera zvakanyanya kurapa ABPA kana kunyangwe yakanyanya asima ine fungal sensitization (SAFS) sezvo zvese zviri kukonzerwa nekuita kune fungal hutachiona hunokonzerwa ne Aspergillus. National Aspergillosis Center ndeimwe yenzvimbo dziri kupinda mukuedzwa kwemishonga mitsva iyi uye vanokodzera kutongwa vachasvikwa kukiriniki, kana kana uchida rumwe ruzivo taura nemaneja wedu wekiriniki miedzo pa. azad.aziz@manchester.ac.uk. Azad yakapa varwere vedu hurukuro pamuedzo uyu pamusangano wedu wevarwere wazvino (Chishanu Nyamavhuvhu 4^th) saka iwe unogona zvakare kuteerera kurekodha (ona chinongedzo pazasi).

Murwere weAspergillosis Neil akapa hurukuro inojekesera mumusangano mumwe chetewo pamusoro pezvakanakira kuva nechubhu yekudyisa (PEG) yakaiswa kuti ibvumidze kuwedzerwa kudya kwako kwamazuva ose. Izvi zvinoshandiswa kana murwere asingakwanisi kuisa huremu uye yakanyanya kutetepa kana kurasikirwa nehuremu. Neil akapfeka mapondo gumi nenhatu mumwedzi mishoma nekuda kwePEG yake uye anokurudzira zvakasimba chero munhu anenge akumbirwa kuti afunge nezvekuva nechubhu yekudyisa kuti aenderere mberi asina kukahadzika. Ndatenda Neil!